منابع مشابه
Genome-wide array analysis of normal and malformed human hearts.
BACKGROUND We present the first genome-wide cDNA array analysis of human congenitally malformed hearts and attempted to partially elucidate these complex phenotypes. Most congenital heart defects, which account for the largest number of birth defects in humans, represent complex genetic disorders. As a consequence of the malformation, abnormal hemodynamic features occur and cause an adaptation ...
متن کاملAnatomic-echocardiographic correlates: an introduction to normal and congenitally malformed hearts.
With a sound understanding of anatomy, detecting and diagnosing most congenital heart malformations with echocardiography need not be an onerous task. Using all the modalities of ultrasound, the examination should define as completely as possible the morphological and physiological aspects of the malformation. The cross sectional imaging modality is a superb tool for displaying the morphology o...
متن کاملThe practical clinical value of three-dimensional models of complex congenitally malformed hearts.
OBJECTIVE Detailed 3-dimensional anatomic information is essential when planning strategies of surgical treatment for patients with complex congenitally malformed hearts. Current imaging techniques, however, do not always provide all the necessary anatomic information in a user-friendly fashion. We sought to assess the practical clinical value of realistic 3-dimensional models of complex congen...
متن کاملDevelopment and evaluation of a computer-based educational program for adults with congenitally malformed hearts.
BACKGROUND There is a lack of educational material for adults with congenitally malformed hearts. Computer-based education has shown to have significant effects on knowledge and management of chronic diseases. AIM The aim of this study was to develop and evaluate a computer-based educational program for adults with congenitally malformed hearts. METHODS The program was developed by a multid...
متن کاملComparison of three dimensional echocardiographic findings with anatomical specimens of various congenitally malformed hearts.
OBJECTIVE To compare the reconstructions obtained by three dimensional echocardiography with the anatomical specimens used to generate the echocardiograms. DESIGN The heart specimens were immersed in a water bath and imaged with a 5 MHz echocardiographic transducer mounted into a scan frame which allowed the transducer to travel a total distance of 4.4 cm in steps of 0.25 mm. The transducer r...
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ژورنال
عنوان ژورنال: Human Mutation
سال: 2005
ISSN: 1059-7794,1098-1004
DOI: 10.1002/humu.9390